To prevent catastrophic climate change, the world needs to reach zero net emissions by midcentury. Achieving that goal will require rapid innovation and large-scale investments in every economic sector, including the massive global food and agriculture economy. Within that sector, the largest single factor determining climate success will be whether the world transitions to low greenhouse gas sustainable protein (SP). Fortunately, the rapidly emerging SP economy provides enormous economic opportunities for U.S. companies, farmers, and workers. American companies are global leaders in low GHG protein innovation and production. While the United States has a natural comparative advantage in SP, other nations are moving quickly to catch up. Strong public policies are needed to maintain U.S. leadership and accelerate innovations that will benefit the American economy and people.